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KMID : 1235520150140040101
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Research in Vestibular Science
2015 Volume.14 No. 4 p.101 ~ p.109
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Genetic Approach of Dizziness
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최재환:Choi Jae-Hwan
저자없음:No authors listed
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Abstract
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Patients with recurrent vertigo/dizziness or unsteadiness are a heterogeneous group of complex disorders affecting the peripheral and central vestibular system. They represent a diagnostic challenge for the clinicians, and their genetic basis is largely not known. However, there are some cerebellar and vestibular disorders with a strong genetic background, such as episodic ataxia, spinocerebellar ataxia, vestibular migraine, Meniere’s disease, and autosomal dominant nonsyndromic deafness. Furthermore, recent advances in next generation sequencing technique are increasing the number of novel genes associated with cerebellar and vestibular disorders. In this article, we have summarized clinical and molecular genetics findings in neuro-otology.
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KEYWORD
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Genetic study, Dizziness, Cerebellar ataxia, Vestibulopathy
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